Grk and Β-arrestin Mediated Desensitization of the Angiotensin Ii Type 1a Receptor Elucidated by Diacylglycerol Dynamics
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چکیده
GRK AND β-ARRESTIN MEDIATED DESENSITIZATION OF THE ANGIOTENSIN II TYPE 1A RECEPTOR ELUCIDATED BY DIACYLGLYCEROL DYNAMICS Jonathan D. Violin, Scott M. DeWire, William G. Barnes, and Robert J. Lefkowitz Department of Medicine and Biochemistry, Duke University Medical Center, and Howard Hughes Medical Institute. * These authors contributed equally to this work. Running Title: Receptor Desensitization Measured by Diacylglycerol Dynamics Address Correspondence to: Robert J. Lefkowitz, Howard Hughes Medical Institute, Duke University Medical Center, Box 3821, Durham, NC 27710 Tel: 919-684-2974; Fax: 919-684-8875; E-mail: [email protected]
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تاریخ انتشار 2006